Illuminating Protection: Photobiomodulation and Stem Cell Therapy Shield Pheochromocytoma Cells from Oxidative Stress

Abstract

This study investigates the protective effects of photobiomodulation (PBM) and stem cell therapy on pheochromocytoma cells subjected to oxidative stress. Pheochromocytoma, a rare neuroendocrine tumor, is known to be susceptible to oxidative damage due to its high metabolic activity. Oxidative stress plays a significant role in the progression and pathogenesis of pheochromocytoma. Photobiomodulation, utilizing low-level light therapy, and stem cell therapy have emerged as promising strategies for mitigating oxidative stress and promoting cellular repair. This review examines the mechanisms underlying the protective effects of PBM and stem cell therapy against oxidative stress in pheochromocytoma cells, focusing on their ability to modulate cellular signaling pathways, enhance antioxidant defenses, and promote cell survival. Furthermore, potential synergistic interactions between PBM and stem cell therapy are explored, offering new insights into combinatorial approaches for managing oxidative stress in pheochromocytoma. Understanding the mechanisms by which PBM and stem cell therapy shield pheochromocytoma cells from oxidative stress may provide valuable therapeutic avenues for improving the management of this challenging disease.